Human Relaxin-2 Recombinant Protein
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Relaxin-2 is a peptide hormone structurally related to insulin, which is expressed in the placenta, decidua, prostate, and in the ovary during pregnancy. Of the three known relaxin genes, Relaxin-2 is the only relaxin known to circulate in the blood. Relaxin-2 binds specifically to the LGR7 and LGR8 receptors, previously identified as an “orphan” G protein coupled receptors. Signaling by Relaxin-2 through its target receptors enhances the growth of pubic ligaments and ripening of the cervix during birth. Recombinant Relaxin-2 is a nonglycosylated 6.0 kDa disulfide linked heterodimeric protein consisting of a 24 amino acid A-chain and a 29 amino acid B-chain.
- Gene name: Relaxin-2
- Host: E. coli
- Label: None
- Applications: Data not available.
- Species Reactivity/Origin species: Human
- Purity: > 98% by SDS-PAGE & HPLC analyses
- Endotoxin levels: < 0.1 ng/µg of protein (<1EU/µg)
- Additives/Stabilizer: None
- Form: lyophilized
- MW: 6.0 kDa
- Length (aa): 53
- Protein Sequence: A-Chain: QLYSALANKC CHVGCTKRSL ARFC
- B-Chain: DSWMEEVIKL CGRELVRAQI AICGMSTWS
- NCBI GeneID: 6019
- Accession Number Protein: NP_005050.2
- Accession Numberm RNA: NM_005059.3
- Uniprot: P04090
For research use only.
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