Human IFN omega Recombinant Protein
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IFN-ω is a type I interferon, which can be induced by virus-infected leukocytes. Members of the type I interferon family, which includes IFN-alpha, IFN-ß, and IFN-ω, signal through IFNAR-1/IFNAR-2 receptor complex, and exert antiviral and antiproliferative activities. IFN-ω exhibits about 75% sequence homology with IFN-alpha, and contains two conserved disulfide bonds, which are necessary for full biological activity. Recombinant Human IFN-ω is a 19.9 kDa protein consisting of 172 amino acid residues.
- Gene name: IFN omega
- Host: E. coli
- Label: None
- Applications: The ED50 was determined by a cytotoxicity assay using Human TF-1 cells is ≤ 0.01 ng/ml, corresponding to a specific activity of ≥ 1 x 108 units/mg.
- Species Reactivity/Origin species: Human
- Purity: > 98% by SDS-PAGE & HPLC analyses
- Endotoxin levels: < 0.1 ng/µg of protein (<1EU/µg)
- Additives/Stabilizer: None
- Form: lyophilized
- MW: 19.9 kDa
- Length (aa): 172
- Protein Sequence: CDLPQNHGLL SRNTLVLLHQ MRRISPFLCL KDRRDFRFPQ EMVKGSQLQK AHVMSVLHEM LQQIFSLFHT ERSSAAWNMT LLDQLHTGLH QQLQHLETCL LQVVGEGESA GAISSPALTL RRYFQGIRVY LKEKKYSDCA WEVVRMEIMK SLFLSTNMQE RLRSKDRDLG SS
- NCBI GeneID: 3467
- Accession Number Protein: NP_002168.1
- Accession Numberm RNA: NM_002177
- Uniprot: P05000
- Chromosomal location: 9p22
For research use only.
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