AMRI-59
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AMRI-59 is a potent inhibitor of PrxI used for parasitic infections. AMRI-59 can increase cellular ROS, leading to activation of signaling pathways mediated by mitochondria and apoptosis signal-regulated kinase 1, thereby leading to apoptosis in A549 human lung adenocarcinoma. AMRI-59 exhibits significant antitumor activity without apparent acute toxicity[1].
- CAS number: 923515-92-8
- Formula: C25H27N3O2
- Solubility: 10 mM in DMSO
- SMILES: O=C(N1CCC(CC2=CC=C(N3C=CC=C3)C=C2)CC1)NC4=CC=CC(C(C)=O)=C4
- Molecular Weight: 401.50
- Applications: COVID-19-immunoregulation
For research use only. Not to be used for human or animal treatment or consumption.
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