6-Diazo-5-oxo-L-nor-Leucine
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6-Diazo-5-oxo-L-nor-Leucine (L-6-Diazo-5-oxonorleucine; DON) is a glutamine antagonist that irreversibly inhibits the catabolic effect of glutamine. 6-Diazo-5-oxo-L-nor-Leucine shows good anticancer activity (especially in pancreatic cancer) and reduces the self-renewal potential and metastatic capacity of tumour cells. 6-Diazo-5-oxo-L-nor-Leucine also possesses antibacterial and antiviral activity[1][2][3].
- CAS number: 157-03-9
- Purity: 99.92
- Formula: C6H9N3O3
- Solubility: H2O : 25 mg/mL (ultrasonic)
- SMILES: N[C@@H](CCC(C=[N+]=[N-])=O)C(O)=O
- Molecular Weight: 171.15
- Applications: Cancer-programmed cell death
-20°C (Powder, sealed storage, away from moisture)
