Trametinib
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Trametinib
- SMILES: CC(=O)Nc1cccc(c1)-n1c2c(C)c(=O)n(C)c(Nc3ccc(I)cc3F)c2c(=O)n(C2CC2)c1=O
- Formula: C26H23FIN5O4
- Purity: 0.9988
- CAS#: 871700-17-3
- Molecular Weight: 615.404
- Bioactivity: Trametinib is an ATP-noncompetitive inhibitor of MEK 1/2 (IC50s: 0.7/0.9 nM). It shows low inhibition for more than 180 kinases, including B-Raf, c-Raf, and MEK5.
For research use only.
