TC-S 7009
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TC-S 7009
- SMILES: O=N(=O)C=1C2=NON=C2C=CC1NC=3C=C(F)C=C(Cl)C3
- Formula: C12H6ClFN4O3
- Purity: 0.98
- CAS#: 1422955-31-4
- Molecular Weight: 308.65
- Bioactivity: TC-S 7009 is more selective for HIF-2α than HIF-1α (Kd 5 μM). TC-S 7009 is an effective and selective inhibitor of HIF-2α (Kd: 81 nM). TC-S 7009 disrupts HIF-2α heterodimerization, decreases DNA-binding activity, and reduces HIF-2α target gene expression.
For research use only.
