SIS3 free base
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SIS3 free base
- SMILES: O=C(C=CC=1C2=CC=CN=C2N(C1C=3C=CC=CC3)C)N4CC5=CC(OC)=C(OC)C=C5CC4
- Formula: C28H27N3O3
- Purity: 0.98
- CAS#: 1009104-85-1
- Molecular Weight: 453.53
- Bioactivity: SIS3 free base is a potent and selective Smad3 phosphorylation inhibitor. SIS3 free base inhibits the myofibroblast differentiation of fibroblasts by TGF-β1.
For research use only.