Anti-Human ALPL Antibody
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There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue-nonspecific). The first three are located together on chromosome 2, whereas the tissue-nonspecific form is located on chromosome 1. The product of this gene is a membrane-bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. The exact physiological function of the alkaline phosphatases is not known. A proposed function of this form of the enzyme is matrix mineralization. However, mice that lack a functional form of this enzyme show normal skeletal development.
- Gene name: ALPL
- Host: Mouse
- Label: None
- Clone: (#4C67)
- Isotype: IgG1
- Applications: WB
- Species Reactivity/Origin species: Human
- Antigen: Native human ALPL
- Purification method: Protein G chromatography
- Reconstitution Buffer: PBS
- Buffer: PBS
- Additives/Stabilizer: None
- Form: lyophilized
- Storage: Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
- Reconstitution tips: Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
- NCBI GeneID: 249
- Accession Number Protein: NP_000469.3
- Accession Numberm RNA: NM_000478.5
- Uniprot: P05186
For research use only.
