TH-Z835
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TH-Z835 is a mutant selective KRAS (G12D) inhibitor with an IC50 of 1.6 μM. TH-Z835 inhibits both mantGMPPNP/GPPNP exchange and GPPNP/mantGMPPNP exchange[1].
- CAS number: 2766209-50-9
- Formula: C30H38N6O
- Solubility: 10 mM in DMSO
- SMILES: CN(CCC1)[C@@H]1COC2=NC(N3C[C@H]4N[C@H](CC4)C3)=C5C(CN(C6=CC=CC7=C6C(C)=CC=C7)CC5)=N2
- Molecular Weight: 498.66
For research use only. Not to be used for human or animal treatment or consumption.
