Reverse transcriptase-IN-1
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Reverse transcriptase-IN-1 (Compound 12z), a diarylbenzopyrimidine (DABP) analogue, is a potent, orally active HIV-1 nonnucleoside reverse transcriptase inhibitor. Reverse transcriptase-IN-1 has antiviral activity with EC50 values of 3.4 nM, 4.3 nM and 3.6 nM for HIV-1 IIIB, E138K and K103N mutants, respectively. Reverse transcriptase-IN-1 also has an IC50of 13.7 nM against HIV-1 reverse transcriptase enzyme[1].
- CAS number: 2380001-43-2
- Purity: 98.08
- Formula: C25H17N7O2
- Solubility: DMSO : 12.5 mg/mL (ultrasonic
- warming
- heat to 60°C)
- SMILES: N#CC1=CC=C(NC2=NC(NC3=C([N+]([O-])=O)C=C(/C=C/C#N)C=C3C)=C4C=CC=CC4=N2)C=C1
- Molecular Weight: 447.45
- Applications: COVID-19-anti-virus
-20°C, 3 years (Powder)
For research use only. Not to be used for human or animal treatment or consumption.
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