Neomycin (sulfate)
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Neomycin sulfate, an aminoglycoside antibiotic, exerts antibacterial activity through irreversible binding of the nuclear 30S ribosomal subunit, thereby blocking bacterial protein synthesis. Neomycin sulfate is a known phospholipase C (PLC) inhibitor. Neomycin sulfate potently inhibits both nuclear translocation of angiogenin and angiogenin-induced cell proliferation and angiogenesis[1][2].
- CAS number: 1405-10-3
- Purity: 98.0
- Formula: C23H52N6O25S3
- Solubility: H2O : 250 mg/mL (ultrasonic)
- SMILES: O[C@H]1[C@H](O)[C@@H](N)[C@@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O)[C@H]2O[C@@H]3O[C@H](CO)[C@@H](O[C@H]4O[C@@H](CN)[C@@H](O)[C@H](O)[C@H]4N)[C@H]3O)O[C@@H]1CN.[3H2SO4]
- Molecular Weight: 908.88
- Applications: COVID-19-immunoregulation
4°C (Powder, sealed storage, away from moisture)
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