Linifanib (GMP)
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Linifanib (ABT-869) (GMP) is Linifanib (HY-50751) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. Linifanib is a potent and orally active multi-target inhibitor of VEGFR and PDGFR family with IC50s of 4, 3, 66, and 4 nM for KDR, FLT1, PDGFRβ, and FLT3, respectively. Linifanib (GMP) promotes the generation and reprogramming of iPSCs from somatic cells[1].
- CAS number: 796967-16-3
- Formula: C21H18FN5O
- Solubility: 10 mM in DMSO
- SMILES: O=C(NC1=CC=C(C2=C3C(N)=NNC3=CC=C2)C=C1)NC4=C(C=CC(C)=C4)F
- Molecular Weight: 375.40
- Applications: Cancer-Kinase/protease
For research use only. Not to be used for human or animal treatment or consumption.
