LE 300
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LE 300 is a potent and selective dopamine D1-like receptor antagonist with Kis of 1.9 nM and 7.5 nM in CHO cell membranes expressing human dopamine D1 and D5 receptors, respectively. LE 300 is an antagonist of the 5-HT2A receptor with a pA2 of 8.32 in a rat tail artery assay[1][2].
- CAS number: 274694-98-3
- Formula: C20H22N2
- Solubility: 10 mM in DMSO
- SMILES: CN1CCC2=C(NC3=C2C=CC=C3)CC4=CC=CC=C4CC1
- Molecular Weight: 290.40
- Applications: Neuroscience-Neuromodulation
For research use only. Not to be used for human or animal treatment or consumption.
