KB-R7943 (mesylate)
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KB-R7943 mesylate is a widely used inhibitor of the reverse Na+/Ca2+ exchanger (NCXrev) with IC50 of 5.7±2.1 µM. KB-R7943 mesylate induces cancer cell death via activating the JNK pathway and blocking autophagic flux.
- CAS number: 182004-65-5
- Purity: 99.16
- Formula: C17H21N3O6S2
- Solubility: DMSO : 100 mg/mL (ultrasonic)
- SMILES: NC(SCCC1=CC=C(OCC2=CC=C([N+]([O-])=O)C=C2)C=C1)=N.CS(=O)(O)=O
- Molecular Weight: 427.50
- Applications: Cancer-programmed cell death
4°C (Powder, sealed storage, away from moisture)
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