IRL 2500
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IRL 2500 is a potent Endothelin receptor antagonist. IRL 2500 shows IC50 values of 1.3 and 94 nM for ETB and ETA receptors, respectively. IRL 2500 inhibits ETB receptor-mediated blood pressure increase and renal vascular resistance in rats in vivo[1].
- CAS number: 169545-27-1
- Purity: 99.0
- Formula: C36H35N3O4
- Solubility: DMSO : 100 mg/mL (ultrasonic)
- SMILES: O=C(O)[C@H](CC1=CNC2=CC=CC=C12)NC([C@@H](CC3=CC=C(C4=CC=CC=C4)C=C3)N(C(C5=CC(C)=CC(C)=C5)=O)C)=O
- Molecular Weight: 573.68
- Applications: Neuroscience-Neuromodulation
4°C (Powder, sealed storage, away from moisture)