ERRα antagonist-2
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ERRα antagonist-2 (Compound 11) is a potential ERRα (estrogen related receptor α) inverse agonist with an IC50 of 0.80 μM. ERRα antagonist-2 suppresses the migration and invasion of the ER-negative MDA-MB-231 cell line. ERRα antagonist-2 inhibits breast cancer growth in vivo[1].
- Formula: C19H16N2O6S
- Solubility: 10 mM in DMSO
- SMILES: COC1=CC=C(C=C1)OC2=CC=CC=C2NS(=O)(C3=CC=C([N+]([O-])=O)C=C3)=O
- Molecular Weight: 400.41
- Applications: Cancer-programmed cell death
For research use only. Not to be used for human or animal treatment or consumption.
