
BLT2 antagonist-1
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BLT2 antagonist-1 (compound 15b) is a selective BLT2 antagonist that inhibits the chemotaxis of CHO-BLT2 cells with an IC50 of 224 nM. BLT2 antagonist-1 does not inhibits the chemotaxis of CHO-BLT1 cells. BLT2 antagonist-1 also inhibits the binding of LTB4 and BLT2 with a Ki value of 132 nM. BLT2 antagonist-1 can be used for the research of the inflammatory airway diseases such as asthma and chronic obstructive pulmonary disease[1].
- CAS number: 2069220-61-5
- Formula: C26H26FNO4
- Solubility: 10 mM in DMSO
- SMILES: O=C(CCCC)N(C1=CC=CC(F)=C1)CC2=CC=C(C3=CC=C(OCC(O)=O)C=C3)C=C2
- Molecular Weight: 435.49
For research use only. Not to be used for human or animal treatment or consumption.