BAY-876
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BAY-876 is an orally active and selective glucose transporter 1 (GLUT1) inhibitor with an IC50 of 2 nM. BAY-876 is >130-fold more selective for GLUT1 than GLUT2, GLUT3, and GLUT4[1]. BAY-876 is also a potent blocker of glycolytic metabolism and ovarian cancer growth[2].
- CAS number: 1799753-84-6
- Purity: 98.46
- Formula: C24H16F4N6O2
- Solubility: DMSO : ≥ 100 mg/mL|Methanol : 1 mg/mL (ultrasonic
- warming
- heat to 60°C)
- SMILES: O=C(C1=NC2=CC(F)=CC=C2C(C(NC3=C(C)N(CC4=CC=C(C#N)C=C4)N=C3C(F)(F)F)=O)=C1)N
- Molecular Weight: 496.42
- Applications: Cancer-programmed cell death
- -20°C, 3 years
- 4°C, 2 years (Powder)