AZD0156
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AZD0156 is a potent, selective and orally active ATM inhibitor with an IC50 of 0.58 nM. AZD0156 inhibits the ATM-mediated signaling, prevents DNA damage checkpoint activation, disrupts DNA damage repair, and induces tumor cell apoptosis[1].
- CAS number: 1821428-35-6
- Purity: 99.82
- Formula: C26H31N5O3
- Solubility: DMSO : 20 mg/mL (ultrasonic
- adjust pH to 3 with HCl)
- SMILES: O=C(N1C2CCOCC2)N(C)C3=C1C4=CC(C5=CC=C(OCCCN(C)C)N=C5)=CC=C4N=C3
- Molecular Weight: 461.56
- Applications: Cancer-Kinase/protease
- -20°C, 3 years
- 4°C, 2 years (Powder)
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