Alpelisib (hydrochloride)
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Alpelisib hydrochloride (BYL-719 hydrochloride) is a potent, orally active, and selective PI3Kα inhibitor with IC50s of 5 nM, 250 nM, 290 nM and 1200 nM for p110α, p110γ, p110δ, and p110β, respectively. Alpelisib hydrochloride (BYL-719 hydrochloride) shows antineoplastic activity[1][2].
- CAS number: 1584128-91-5
- Formula: C19H23ClF3N5O2S
- Solubility: 10 mM in DMSO
- SMILES: CC(N=C(S1)NC(N2CCC[C@H]2C(N)=O)=O)=C1C3=CC(C(C)(C(F)(F)F)C)=NC=C3.Cl
- Molecular Weight: 477.93
- Applications: Cancer-Kinase/protease
For research use only. Not to be used for human or animal treatment or consumption.
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