2’-Azido-2’-deoxy-5-methyl cytidine
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2’-Azido-2’-deoxy-5-methyl cytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. 2’-Azido-2’-deoxy-5-methyl cytidine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
- CAS number: 2095417-75-5
- Formula: C10H14N6O4
- Solubility: 10 mM in DMSO
- SMILES: OC[C@@H]1[C@@H](O)[C@@H](N=[N+]=[N-])[C@H](N2C(N=C(N)C(C)=C2)=O)O1
- Molecular Weight: 282.26
- Applications: Cancer-programmed cell death
For research use only. Not to be used for human or animal treatment or consumption.
