Onchocerca volvulus OV16 protein, GST Tag
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Onchocerca volvulus OV16, GST Tag (OV6-V51G4) is expressed from E. coli cells. It contains AA Lys 17 - Asp 197 (Accession # P31729-1).
The OV16 antigen, localizes to the hypodermis, cuticle, and uterus of female O. volvulus is regarded as a highly sensitive and specific antigen for detection of IgG4 in people with prior exposure to onchocerciasis. It has an open reading frame that encodes a 152- amino acid polypeptide containing a 16-amino acid putative signal peptide. Enzyme-linked Immunosorbent Assay serological testing of OV-16 antigen is a diagnostic tool for determining effective elimination of the parasite.
Onchocerca volvulus
-20℃ RT
This protein carries a GST tag at the N-terminus. The protein has a calculated MW of 46.8 kDa. The protein migrates as 45 kDa under reducing (R) condition (SDS-PAGE).
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