(R, S)-Niguldipine HCl, Ca2+ channel blocker

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Catalog numberSIH-319-50MG
Name(R, S)-Niguldipine HCl, Ca2+ channel blocker
Size50 mg
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Stock availabilitIn StockIn Stock
CAS number119934-51-9
DescriptionCa2+ channel blocker
Molecular weight646,18 g/mol
Primary research fieldsNeuroscience, Ion Channels, Calcium Channels, Voltage-Gated Calcium Channels
Other name(R,S)-1,4-Dihydro-2,6-dimethyl-4-(3-n­itrophenyl)-3,5-pyridinedicarboxylic acid, 3-(4,4-diphenyl-1-piperidinyl)propyl methyl ester hydrochloride
Product categorySmall Molecules
Product typeInhibitor
Chemical formulaC36H39N3O6•HCl
Purity pourcentage>98%
Soluble inSoluble to 10 mM in water
Physical appearanceYellow solid
Storage recommendations-20ºC
Shipping recommendationsShipped Ambient
Safety informationClassification: Caution: Substance not yet fully tested. Safety Phrases: S22 - Do not breathe dust S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection S24/25- Avoid contact with shin and eyes
PubChem numberRefer to PubChem
Scientific contextNiguldipine is a calcium channel blocker and an a1-adrenergic receptor antagonist.
Bibliography1. Boer R., Grassegger A., Schudt C., Glossman H. (1999) Eur J Pharmacol. 172(2): 131-145. 2. Robinson J.P., Kendall D.A. (1990) Br J Pharmacol. 100(1): 3-4.
Release date8-Apr-2011
PubMed numberRefer to PubMed
Tested applicationsTo be tested
Tested reactivityTo be tested
Representative figure legendChemical structure of (R, S)-Niguldipine HCl (SIH-319), a L-type Ca channel blocker. CAS #: 113317-61-6. Molecular Formula: C36H39N3O6.HCl. Molecular Weight: 646.18 g/mol. Chemical structure of (R, S)-Niguldipine HCl, a L-type Ca channel blocker (SIH-319). CAS # 113317-61-6. Molecular Formula: C36H39N3O6.HCl.
Warning informationNon-hazardous
Country of productionCanada
Total weight (kg)0.25
Net weight (g)0.05