Amlodipine, L-type Ca channel blocker

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Catalog numberSIH-315-50MG
NameAmlodipine, L-type Ca channel blocker
Size50 mg
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Stock availabilitIn StockIn Stock
CAS number111470-99-6
DescriptionL-type Ca channel blocker
Molecular weight567,05 g/mol
Primary research fieldsNeuroscience, Ion Channels, Calcium Channels, Voltage-Gated Calcium Channels
Other name3-Ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydro-3,5-pyridinedicarboxylate, Norvasc
Product categorySmall Molecules
Product typeInhibitor
Chemical formulaC20H25ClN2O5•C6H5SO3H
Purity pourcentage>98%
Soluble inSoluble to 100 mM in DMSO and to 10 mM in water
Physical appearanceWhite Solid
Storage recommendations-20ºC
Shipping recommendationsShipped Ambient
Safety informationClassification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection Risk Phrases: R22 - Harmful if swallowed R62 - Possible risk of impaired fertility Hazard Phrases: H302-H315-H319-H335 Precautionary Phrases: P261-P305 + P351 + P338
PubChem number2162
Scientific contextAmlodipine is a long-acting calcium channel blocker used as an anti-hypertensive and in the treatment of angina. It acts by relaxing the smooth muscle in the arterial wall, decreasing total peripheral resistance and hence reducing blood pressure.
Bibliography1. Luksa J., Josic D., Kremser M., Kopitar Z and Milutinovic S. (1997) J Chromatorgraphy. B, Biomed Sci and App. 693(2): 367-375. 2. Bahl V.K., Jadhav U.M., Thacker H.P. (2009) Am J Cardiovasc Drugs. 9(3): 135-142.
Release date8-Apr-2011
PubMed numberRefer to PubMed
Tested applicationsTo be tested
Tested reactivityTo be tested
Representative figure legendChemical structure of Amlodipine (SIH-315), a L-type Ca channel blocker. CAS #: 111470-99-6. Molecular Formula: C20H25ClN2O5 · C6H5SO3H . Molecular Weight: 567.05 g/mol. Chemical structure of Amlodipine, a L-type Ca channel blocker (SIH-315). CAS # 111470-99-6. Molecular Formula: C20H25ClN2O5 · C6H5SO3H .
Warning informationNon-hazardous
Country of productionCanada
Total weight (kg)0.25
Net weight (g)0.05