AP-18, TRPA1 blocker

Information and details about product


Catalog numberSIH-310-10MG
NameAP-18, TRPA1 blocker
Size10 mg
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Stock availabilitIn StockIn Stock
CAS number55224-94-7
DescriptionTRPA1 blocker
Molecular weight209,67 g/mol
Primary research fieldsNeuroscience, Ion Channels, Transient Receptor Potential Channels
Other name(2E,3E)-4-(4-Chlorophenyl)-N-hydroxy-3-methyl-3-buten-2-imine
Product categorySmall Molecules
Product typeInhibitor
Chemical formulaC11H12ClNO
Purity pourcentage>98%
Soluble inSoluble to 100 mM in DMSO and to 100 mM in ethanol
Physical appearanceWhite Solid
Storage recommendations-20ºC
Shipping recommendationsShipped Ambient
Safety informationClassification: Caution: Substance not yet fully tested. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection Hazard Phrases: H302
PubChem number16725814
Scientific contextAP-18 is a reversible TRPA1 channel blocker. They exhibit fibroblast-like morphology, slow growth and contact inhibition (1).
Bibliography1. Doi H., et al. (2005) Tohoku J Exp Med. 207(3): 209-216.
Release date8-Apr-2011
PubMed numberRefer to PubMed
Tested applicationsTo be tested
Tested reactivityTo be tested
Representative figure legendChemical structure of AP-18 (SIH-310), a TRPA1 blocker. CAS #: 55224-94-7. Molecular Formula: C11H12ClNO. Molecular Weight: 209.67 g/mol. Chemical structure of AP-18, a TRPA1 blocker (SIH-310). CAS # 55224-94-7. Molecular Formula: C11H12ClNO.
Warning informationNon-hazardous
Country of productionCanada
Total weight (kg)0.25
Net weight (g)0.01