BCTC, TRPV1 blocker

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Information

Catalog numberSIH-307-10MG
NameBCTC, TRPV1 blocker
Size10 mg
Price193.00EUR
SKU01012511703
Supplierstressma
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Details

Stock availabilitIn StockIn Stock
CAS number393514-24-4
DescriptionTRPV1 blocker
Molecular weight372,89 g/mol
Primary research fieldsNeuroscience, Ion Channels, Transient Receptor Potential Channels
Other name4-(3-Chloro-2-pyridinyl)-N-[4-(2-methyl-2-propanyl)phenyl]-1-piperazinecarboxamide
Product categorySmall Molecules
Product typeInhibitor
Chemical formulaC20H25ClN4O
OriginSynthetic
Purity pourcentage>98%
Soluble inSoluble to 100 mM in DMSO and to 40 mM in ethanol
Physical appearanceWhite Solid
Storage recommendations-20ºC
Shipping recommendationsShipped Ambient
Safety informationClassification: Caution: Substance not yet fully tested. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
PubChem number9929425
Scientific contextBCTC is an inhibitor of capsaicin- and acid-mediated currents at rat VR1. Thus it has effects on acute, inflammatory and neuropathic pain in rats (1, 2).
Bibliography1. Pomonis J.D., et al. (2003) J Pharmacol Exp Ther. 306(1): 387-393. 2. Valenzano K.J., et al. (2003) J Pharmacol Exp. Ther. 306(1): 377-386.
Release date8-Apr-2011
PubMed numberRefer to PubMed
Tested applicationsTo be tested
Tested reactivityTo be tested
Representative figure legendChemical structure of BCTC (SIH-307), a TRPV1 blocker. CAS #: 393514-24-4. Molecular Formula: C20H25ClN4O. Molecular Weight: 372.89 g/mol. Chemical structure of BCTC, a TRPV1 blocker (SIH-307). CAS # 393514-24-4. Molecular Formula: C20H25ClN4O.
Warning informationNon-hazardous
Country of productionCanada
Total weight (kg)0.25
Net weight (g)0.01