ERRα antagonist-1

ERRα antagonist-1

Der Lieferant: Gentaur

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Katalognummer: 931-T11230-1mg

Größe: 1mg

ERRα antagonist-1

SMILES: N1=C(SCC1)N2C(=NC3C=4C=CC=CC4C=CC=5C=CC=CC53)SCC2
Formula: C21H19N3S2

Purity: 1
CAS#: 1072145-33-5
Molecular Weight: 377.52
Bioactivity: ERRα antagonist-1 is a selective and high affinity estrogen-related receptor α (ERRα) antagonist. ERRα antagonist-1 inhibits interaction of ERRα with Proliferator-activated Receptor γ Coactivator-1α (PGC-1α) and PGC-1β, the IC50 values are 170 nM and 180 nM, respectively. ERRα antagonist-1 does not inhibit the interaction of either ERRβ or ERRγ with PGC-1α and PGC-1β coactivator, and also does not inhibit interaction of ERα or ERβ with PGC-1α or SRC-1.

For research use only.

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