CDK9 Antagonist-1
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CDK9 Antagonist-1
- Purity: 0.98
- Bioactivity: CDK9 Antagonist-1 (compounds 11c) is a potent and selective CDK9 degrader based on PROTAC, with an IC50 of 17 μM in MCF-7 cell lines. Natural product Wogonin binds ubiquitin E3 ligase cereblon (CRBN) via a linker to form PROTAC[1].
For research use only.