Monoclonal antibody for Phosphothreonine
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A monoclonal antibody from clone 18F6 against Human | Mouse | Rat Phosphothreonine. The host species for the production of this antibody is Mouse. The antigen used for immunization is Phosphothreonine conjugated to KLH. The antibody is tested and validated for WB, ICC/IF, ELISA assays with the following recommended dilutions: WB (1:100), ICC/IF (1:100). This MAb for Phosphothreonine is conjugated with APC.
- Protein phosphorylation is an important posttranslational modification that serves many key functions to regulate a protein's activity, localization, and protein-protein interactions. Phosphorylation is catalyzed by various specific protein kinases, which involves removing a phosphate group from ATP and covalently attaching it to to a recipient protein that acts as a substrate. Most kinases act on both serine and threonine
- others act on tyrosine, and a number (dual specificity kinases) act on all three. Because phosphorylation can occur at multiple sites on any given protein, it can therefore change the function or localization of that protein at any time (1). Changing the function of these proteins has been linked to a number of diseases, including cancer, diabetes, heart disease, inflammation and neurological disorders (2-4).
- Shipped on ice packs at +4ºC . Upon receiving the antibody store it at 4ºC.
- The gross weight of the package is 1.4 kg. and the net weight of the product is 0.1 grams.
- The item is not hazardous according to both ADR and UN. Its tariff code is 3002.15.0000 (Immunological products, put up in measured doses or in forms or packings for retail sale). The UNSPSC code of the product is 12352203 (Antibodies).
This product is not for human or animal treatment or consumption. Not for use in diagnostics or therapeutics. For in vitro research use only.