Trametiglue
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Trametiglue, a derivative of Trametinib (HY-10999), targets both KSR-MEK and RAF-MEK with unprecedented potency and selectivity via unique interfacial binding interactions[1].
- CAS number: 2666940-97-0
- Purity: 98.58
- Formula: C25H24FIN6O5S
- Solubility: DMSO : 100 mg/mL (ultrasonic
- warming
- heat to 60°C)
- SMILES: O=C1C2=C(N(C)C(C(C)=C2N(C3=CC(NS(=O)(NC)=O)=CC=C3)C(N1C4CC4)=O)=O)NC5=CC=C(C=C5F)I
- Molecular Weight: 666.46
- -20°C, 3 years
- 4°C, 2 years (Powder)
For research use only. Not to be used for human or animal treatment or consumption.