Cabozantinib-d4
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Cabozantinib-d4 is deuterium labeled Cabozantinib. Cabozantinib is a potent multiple receptor tyrosine kinases (RTKs) inhibitor that inhibits VEGFR2, c-Met, Kit, Axl and Flt3 with IC50s of 0.035, 1.3, 4.6, 7 and 11.3 nM, respectively.
- CAS number: 1802168-53-1
- Formula: C28H20D4FN3O5
- Solubility: 10 mM in DMSO
- SMILES: COC(C(OC)=C1)=CC2=C1C(OC(C=C3)=CC=C3NC(C4(CC4)C(NC5=C([2H])C([2H])=C(C([2H])=C5[2H])F)=O)=O)=CC=N2
- Molecular Weight: 505.53
- Applications: Cancer-Kinase/protease
For research use only. Not to be used for human or animal treatment or consumption.