ELISA kit for Rat Matrix metallopeptidase 8 (MMP8)

MMP8 degrades fibrillar collagens types I, II, III, aggrecan, serpins and alpha 2 macroglobulin. The substrate specificity of collagenases is variable: MMP1 degrades type III collagen more efficiently than type I or type II collagen, whereas MMP8 is more potent in degrading type I collagen than type III or type II collagen. Unlike other members, MMP8 is expressed exclusively in inflammatory conditions. MMP8 is highly expressed in the postpartum uterus, and it is thought to be involved in the postpartum involution of the uterus. MMP8 is also the predominant collagenase expressed in ulcers and healing wounds. MMP8 is very similar to MMP1, sharing 57 % amino acid identity. MMP8 is heavily glycosylated, and the zymogen has a mass of 85 Kd.

• Reactivity: Rat
• Sample types: serum, whole blood, plasma and other biological fluids
• Detection range: Please inquire
• Sensitivity: Please inquire Quantitative Sandwich ELISA
• Method of detection: Colorimetric

All of the components are shipped on ice packs/blue ice. Upon receiving the kit keep it at +4 degrees Celsius for up to 1 year (refer to the label on the box for the exact expiration date).

This kit is intended for research use only. It should not be used for human or animal clinical diagnostics or treatment.